??? Of course their injuries are an excuse...Derek Carr would have lit our defense up (given our injuries like you say), it's a much more significant loss. Sure we lost Brandon Williams and a few others but we invested so much if our offseason on defensive depth and 1 person out makes us go from stout to average on D, you would think we could have some people step up but even before we lost Carl Davis we were getting gashed...You watch that Pittsburgh game? Leveon dropped 150 on us.
Ej Manuel threw a DUCK on a 100mile wide open Crabtree in the Endzone, Carr would have hit him.
We still got Suggs, Mosley, Solid D-linemen(on paper but apparently not really) Weddle Jefferson, and 3 solid CBs...so I'm not gonna make immense excuses. Like Harbaugh says- we have the talent, we just have to perform better. And luckily we did ok against a backup QB, I just don't think a healthy Brandon Williams would have made a world of a difference.